Opioid Receptor Modulation of Gabaergic and Serotonergic Spinally-projecting Neurons Of
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چکیده
Opioid receptor modulation of GABAergic and serotonergic spinally-projecting neurons of 1 the rostral ventromedial medulla in mice 2 3 Abbreviated title: Opioid modulation of GABAergic neurons in the RVM 4 5 Authors: 6 Nigel P. Pedersen (1,2), Christopher W. Vaughan (2), MacDonald J. Christie (1) 7 8 Affiliations: 9 (1) Brain & Mind Research Institute, University of Sydney, NSW 2006, Australia, and 10 (2) Pain Management Research Institute, Kolling Institute of Medical Research, Northern 11 Clinical School, University of Sydney at Royal North Shore Hospital, NSW 2065, Australia. 12 13 Corresponding author: 14 Prof. Macdonald J. Christie 15 Brain & Mind Research Institute, M02G, 16 University of Sydney, Sydney NSW 2006, 17 Australia 18 Ph: + 61 2 9351 0899 19 Fax: +61 2 9114 4015 20 E-mail: [email protected] 21 22 Articles in PresS. J Neurophysiol (May 18, 2011). doi:10.1152/jn.01062.2010
منابع مشابه
Opioid receptor modulation of GABAergic and serotonergic spinally projecting neurons of the rostral ventromedial medulla in mice.
The rostral ventromedial medulla (RVM) is an important site of opioid actions and forms part of an analgesic pathway that projects to the spinal cord. The neuronal mechanisms by which opioids act within this brain region remain unclear, particularly in relation to the neurotransmitters GABA and serotonin. In the present study, we examined serotonergic and GABAergic immunoreactivity, identified ...
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